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Excess iron can induce testicular injury
Unlike peptides, a small molecule sometimes provides the possibility of one or more solid forms
The endogenous enzyme DPP-4 specifically recognizes and enzymatically cleaves peptides that feature an alanine or a proline at the penultimate N-terminal position, rapidly rendering the hormones inactive
In clinical trials, it has been tested at doses ranging from 1mg to 12mg, with a gradual titration schedule designed to reduce gastrointestinal side effects
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